Couples often ask me: “What else can we do to make this IVF cycle successful?” The first answer, is to pick the right lab. I’m fortunate to work with an amazing group of embryologists so I encourage my patients to consider the next step: using your diet and lifestyle to stack the odds in your favor. As we have discussed before in the blog, what you eat and what you do can absolutely impact your fertility and overall health. New research demonstrates that your diet, in particular, can impact your success with IVF.
As many of my patients know, I encourage a plant-based diet to enhance your fertility naturally. The problem with many of these studies that we have previously reviewed is that people who eat a plant-based diet are more likely to be thin and the following question emerges: “Is diet really impacting your fertility or does this have to do with your weight?” A new study helps us address this question.
In this study, women who had a normal weight (BMI < 30 kg/m2) underwent IVF in Greece. Women who ate a Mediterranean diet were more likely to get pregnant and bring home a healthy child compared to women who did not eat a Mediterranean diet. Women who ate better were almost 3 times as likely to bring home a child than women who did not eat a Mediterranean diet! The results suggest that dietary modifications may help increase the chances of a successful pregnancy and delivering a live baby for women undergoing IVF treatment.
What this study doesn’t answer, however, is when these dietary changes need to be implemented in order to have the full benefits on your fertility. My advice is simple: the sooner the better. The healthier you are when you start an IVF cycle, the more likely you are to get the full benefits of diet on your fertility. However, if you have a time crunch with regards to your fertility, with diagnoses such as diminished ovarian reserve, it may not be in your best interest to delay starting treatment. Talk to your doctor for more information about what the best next steps are for you.
Take home points:
- Your diet can impact your chance of having success with IVF
- Consider implementing a Mediterranean diet
- Talk to your doctor for more information to help select the best diet for your goals
We have previously discussed in this blog the impact of the beverages we drink on fertility.The old saying of “You are what you eat” couldn’t be more true- what you eat absolutely impacts how we feel and our overall health.
New research is adding to this old saying- what you drink may be just as important as what you eat, when it comes to fertility. Similarly, we also discussed that the beverages you consume now can impact the health of your future children: women that drank beverages with low-calorie sweeteners are more likely to have obese children.
New research adds to these concerns. In this large study, the dietary habits of men and women were evaluated while they tried to conceive. Drinking sugary beverages was associated with decreased fertility for both men and women. Similarly, participants who had consumed the most sugary drinks (>7 servings/week) were found to have the lowest odds of fertility for both men and women.
This study looked at what couples drank during an IVF cycle and monitored their outcomes. They found that couples that drank more sugary drinks like soda did worse in IVF, when compared to couples who don’t drink sugary drinks: fewer eggs and fewer good quality embryos.
Take home points:
- Men and women should avoid sugary drinks when trying to conceive, but particularly if they are using IVF
- Using artificial sweeteners is not necessarily a safe alternative to sugary drinks
- If you can’t completely eliminate sugary drinks, consider limiting your intake to <1 beverage a day.
A common question asked in a new fertility evaluation is: “Which prenatal vitamin is best?” We have previously tried to provide some guidance in choosing the best vitamin. The ingredient list in your prenatal vitamin needs to be considered.
In particular, iodine is an often-overlooked but extremely important component that should be considered in a prenatal vitamin. Iodine is a mineral used by the body to regulate metabolism; it is also very important for brain development in children. It is often found in seafood, iodized salt, dairy, and some fruits and vegetables.
A new study shows that women who have low iodine levels take longer to get pregnant than women who have normal iodine levels.
Take home points:
- Iodine is important in pregnancy and when you are trying to conceive
- Boost your fertility naturally with iodine
- Make sure you are on a good prenatal vitamin
- Talk to your doctor about what levels of iodine are best for you
We here at the blog are big proponents of vitamin D supplementation to enhance your fertility. New research suggests that vitamin D supplementation may also be important for couples that have difficulty staying pregnant, also known as recurrent pregnancy loss (RPL). One of the causes of RPL has been attributed to an autoimmune condition. In this study, researchers evaluated the immune cells thought to be involved in pregnancy loss. They found that women who had low levels of Vitamin D were more likely to have abnormalities in the immune cells involved in pregnancy loss. This suggests that vitamin D supplementation may be a tool we can use to reduce the risk of pregnancy loss.
What you can do:
- Check your vitamin D before trying to conceive
- Talk to your physician about the evaluation of RPL and treatment options if you have had two ore more pregnancy losses.
Bisphenol A (BPA) is commonly found in plastics and the majority of us are exposed to this hormone disruptor multiple times daily. We previously introduced BPA and the negative health impacts here. We know that BPA exposure when trying to conceive can negatively impact multiple aspects of your health, including your fertility and the likelihood of your children having health problems.
New basic science research is adding to our previous concerns about this endocrine disrupting chemical:
- BPA negatively impacts how an egg matures and egg quality by increasing DNA damage and oxidative stress. This study also shows the potential for the damage that BPA causes for mom to impact her future children.
- BPA can decrease sperm count in males and lead to neurodevelopment problems in their children. This study also was associated with increased obesity in female offspring.
What you can do:
- Switch to BPA free drinking bottles like those with a #5 stamped on them or use either glass or metal instead;
- Purchase soups and foods packaged in cardboard cartons or glass instead of the plastic lined cans;
- Hand wash plastic dishware with mild soap in warm water instead of using dishwashers for these products;
- Don’t place plastic ware in microwave ovens to warm;
- Express your support to companies that are voluntarily phasing out the use of BPA in their products.
I am incredibly proud to work at a REI clinic that has the highest live birth rate in the country. A recent study, however, suggests that IVF may not be enough. Lifestyle and the environment can impact your IVF success rates, even at a top notch REI clinic.
In this study, levels of pesticides and common pollutants were measured in the fluid that was obtained from the ovary during an egg retrieval. They found that higher levels of Pretilachlor, β-cyfluthrin, PCB 28 and 180 was associated with fewer eggs at retrieval, lower fertilization rates, and impaired embryo development. They also found that high PCB and pesticide concentrations negatively affected embryological outcomes. This study provides evidence that these harmful chemicals are found in the fluid surrounding individual eggs and are associated with decreased success with IVF. This suggests that if you want the very best chances of success with IVF, you should consider optimizing your lifestyle to minimize exposure to these harmful chemicals.
What you can do:
- Learn how to minimize your exposure to PCBs and pesticides
- Make a plan to optimize your health before you invest in an IVF cycle
- Talk to your doctor about a timeline for implementing these changes
I spend a considerable amount of time working with my patients to prepare them for a healthy pregnancy. Lifestyle modifications like small changes to your diet and environment can absolutely optimize your chances of conceiving, regardless of what kind of treatment you are undergoing. This blog is dedicated to exploring the research behind our recommendations to couples.
I want to share an additional helpful resource to those of you who are trying to initiate these lifestyle changes. This group helps you tackle lifestyle changes, one room at a time in a user friendly and interactive manner. Check them out!